I finally finished upgrading my blog to Twitter Bootstrap 2 today. I also significantly improved comments, so leave a comment!
As a non-designer, I really appreciate Bootstrap – it is a great tool. My biggest gripe about creating web apps is that there are no basic UI components available out of the box. Every other major desktop and mobile platform has core components that get you off the ground. Bootstrap solves this problem for the web.
If there is one drawback to Bootstrap, I imagine a zoo of web sites (like my own) launching very soon that all use the basic Bootstrap templates, which might lead to the generification (I just made that word up!) of the web. But I suspect it won’t be long before there are Bootstrap themes which would provide the best of both worlds – a common UI toolkit with custom designs.